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研究成果


  • 平成23(2011)年度

  • 発表論文

    1. Aikawa, S., Izumi, Y., Matsuda, F., Hasunuma, T., Chang, J. S., Kondo, A.:Synergistic enhancement of glycogen production in Arthrospira platensis by optimization of light intensity and nitrate supply, Bioresource Technology, 108, 211-215, (2012)
    2. Matano, Y., Hasunuma, T., Kondo, A.:Display of cellulases on the cell surface of Saccharomyces cerevisiae affords high yield ethanol production from high-solid lignocellulosic biomass, Bioresource Technology, 108, 128-133, (2012)
    3. Madhavan, A., Srivastava, A., Kondo, A., Bisaria, V.:Bioconversion of lignocellulose-derived sugars to ethanol by engineered Saccharomyces cerevisiae, Critical Review in Biotechnology, 32(1), 22-48, (2012)
    4. Sugimori, D., Matsumoto, Y., Tomita, Y., Murayama, K., Ogino, C.:Kinetic characterization and Mg2+ enhancement of Streptomyces griseocarneus sphingomyelinase C produced by recombinant Streptomyces lividans, Protein Expression and Purification, 81(2), 151-156, (2012)
    5. Noda, S., Miyazaki, T., Tanaka, T., Ogino, C., Kondo, A.:Production of Streptoverticillium cinnamoneum transglutaminase and cinnamic acid by recombinant Streptomyces lividans cultured on biomass-derived carbon sources, Bioresource Technology, 104, 648-651 (2012)
    6. Nakamura, T., Tokushima, T., Kawabata, K., Yamamoto, N., Miyamoto, M., Ashida. H.:Absorption and metabolism of 4-hydroxyderricin and xanthoangelol after oral administration of Angelica keiskei (Ashitaba) extract in mice, Archives of Biochemistry and Biophyscs, 521(1-2), 71-76, (2012)
    7. Sawada, K., Kawabata, K., Yamashita, T., Kawasaki, K., Yamamoto, N., Ashida. H.:Ameliorative effects of polyunsaturated fatty acids against palmitic acid-induced insulin resistance in L6 skeletal muscle cells, Lipids in Health and Disease, 11(1), (2012)
    8. 山下陽子,山本憲朗,芦田均:「ポリフェノールによるグルコーストランスポーターの機能調節 Functional regulation of glucose transporters by polyphenol 」,日本ビタミン学会誌,86 3 , 163-173, (2012)
    9. Yamashita, Y., Okabe, M., Natsume, M., Ashida. H.:Comparison of anti-hyperglycemic activities between low- and high-degree of polymerization procyanidin fractions from cacao liquor extract, Journal of Food and Drug Analysis, 20, 283-287, (2012)
    10. Hara, K.Y., Kim, S., Yoshida, H., Kiriyama, K., Kondo, T., Okai, N., Ogino, C., Fukuda, H., Kondo, A.:Development of a glutathione production process from proteinaceous biomass resources using protease-displaying Saccharomyces cerevisiae, Applied Microbiology and Biotechnology, 93(4), 1495-1502, (2012)
    11. Matsumoto T., Tanaka T., Kondo, A.:Sortase A-catalyzed site-specific co-immobilization on microparticles via streptavidin, Langmuir, 28(7), 3553-3557, (2012)
    12. Razi, F., Sawada, I., Ohmukai, Y., Maruyama, T., Matsuyama, H.:The improvement of antibiofouling efficiency of polyethersulfone membrane by functionalization with zwitterionic monomers, Journal of Membrane Science, 401-402, 292-299, (2012)
    13. Razi, F., Sawada, I., Ohmukai, Y., Maruyama, T., Matsuyama, H.:Surface functionalization by grafting of (2-dimethylamino) ethyl methacrylate methyl chloride quaternary salt (DMAEMAq) onto hollow fiber polyethersulfone (PES) membranes for improvement of antibiofouling properties, Solvent Extraction Research and Development, 19, 101-115, (2012)
    14. Sawada, I., Fachrul, R., Ito, T., Ohmukai, Y., Maruyama, T., Matsuyama, H.:Development of a hydrophilic polymer membrane containing silver nanoparticles with both organic antifouling and antibacterial properties, Journal of Membrane Science, 387, 1-6, (2012)
    15. Yamamoto, N., Kawabata, K., Sawada, K., Ueda, M., Fukuda, I., Kawasaki, K., Murakami, A., Ashida, H.:Cardamonin stimulates glucose uptake through translocation of glucose transporter-4 in L6 myotubes, Phytotherapy Research, 25(8), 1218-1224, (2011)
    16. Hama, S., Tamalampudi, S., Yoshida, A., Tamadani, N., Kuratani, N., Noda, H., Fukuda, H., Kondo, A.:Process engineering and optimization of glycerol separation in a packed-bed reactor for enzymatic biodiesel production, Bioresource Technology, 12, 10419-10424, (2011)
    17. Noda, S., Miyazaki, T., Miyoshi, T., Miyake, M., Okai, N., Tanaka,T., Ogino, C., Kondo, A. :Cinnamic acid producion using phenylalanine ammonia lyase expressing Streptomyces lividans, Journal of Industrial Microbiology and Biotechnology, 38(5), 643-648, (2011)
    18. Yoshida, S., Okano, K., Tanaka, T., Ogino, C., Kondo, A.:Homo d-lactic acid production from xylose/glucose mixture using xylose-assimilating operon integrated Lactobacillus plantrum, Applied Microbiology and Biotechnology, 92(1), 67-76, (2011)
    19. Yoshida, H., Hara K.Y., Kiriyama, K., Nakayama, H., Okazaki, F., Matsuda, F., Ogino, C., Fukuda, H., Kondo, A. :Enzymatic glutathione production using metabolically engineered Saccharomyces cerevisiae as a whole-cell biocatalyst, Applied Microbiology and Biotechnology, 91(4), 1001-1006, (2011)
    20. Furuyashiki, T., Takata, H., Kojima, I., Kuriki, T., Fukuda, I., Ashida, H.:Metabolic fate of orally administered enzymatically synthesized glycogen in rats, Food & Function, 2(3-4), 183-189, (2011)
    21. Nakashima, K., Yamaguchi, K., Taniguchi, N., Arai, S., Yamada, R., Katahira, S., Ishida, N., Takahashi, H., Ogino, C., Kondo, A.:Direct bioethanol production from cellulose by the combination of cellulase displaying yeast and ionic liquid pretreatment, Green Chemistry, 13(10), 2948-2953, (2011)
    22. Sanda, T., Hasunuma, T., Matsuda, F., Kondo, A.:Repeated-batch fermentation of lignocellulosic hydrolysate to ethanol using a hybrid Saccharomyces cerevisiae strain metabolically engineered for tolerance to acetic and formic acids, Bioresource Technology, 102, 7917-7924, (2011)
    23. Hama, S., Tamalampudi, S., Yoshida, A., Tamadani, N., Kuratani, N., Noda, H., Fukuda, H., Kondo, A.:Enzymatic packed-bed reactor integrated with glycerol-separating system for solvent-free production of biodiesel fuel, Biochemical Engineering Journal, 55, 66-71, (2011)
    24. Yamada, R., Taniguchi, N., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A.:Direct ethanol production from cellulosic materials using a cellulolytic enzymes expression optimized diploid Saccharomyces cerevisiae strain, Biotechnology for production of Fuels, 4, 8, (2011)
    25. Adachi, D., Hama, S., Numata, T., Nakashima, K., Ogino, C., Fukuda, H., Kondo, A.:Development of an Aspergillus oryzae whole-cell biocatalyst coexpressing triglyceride and partial glyceride lipases for biodiesel production, Bioresource Technology, 102(12), 6723-6729, (2011)
    26. Hama, S., Miura, K., Yoshida, A., Noda, H., Fukuda, H., Kondo, A.:Transesterification of phosphatidylcholine in sn-1 position through direct use of lipase-producing Rhizopus oryzae cells as whole-cell biocatalylst, Applied Microbiology and Biotechnology, 90(5), 1731-1738, (2011)
    27. Yamada, R., Yamakawa, S., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A.:Direct and efficient ethanol production from high-yielding rice using a Saccharomyces cerevisiae strain that express amylases, Enzyme and Microbial Technology, 48, 393-396, (2011)
    28. Yoshida, A., Hama, S., Nakashima, K., Kondo, A.:Water activity dependence of performance of surface-displayed lipase in yeast cells: A unique water requirement for enzymatic synthetic reaction in organic media, Enzyme and Microbial Technology, 48, 334-338, (2011)
    29. Matsuda, F., Hayashi, M., Kondo, A.:Comparative profiling anlysis of central metabolites in Euglena gracilis under various cultivation conditions, Bioscience, Biotechnology, and Biochemistry, 75(11), 2253-2256, (2011)
    30. Matsuda, F., Yamasaki, M., Hasunuma, T., Ogino C., Kondo, A.:Variation in biomass property among rice diverse cultivars, Bioscience, Biotechnology, and Biochemistry, 75(8), 1603-1605, (2011)
    31. Nakamura, T., Tanaka, R., Ashida, H.:Possible evidence of the contamination by catechins in deconjugation enzymes from Helix pomatia and Abalone entrails,Bioscience, Biotechnology, and Biochemistry, 75(8), 1506-1510, (2011)
    32. Imada, S., Tanaka, A., Nishiumi, S., Ashida, H.:Concentration of catechins and caffeine in black tea affect suppression of fat accumulation and hyperglycemia in high-fat diet-fed mice, Food Science and Technology Research, 17(4), 353-359, (2011)
    33. Nishiumi, S., Bessyo, H., Kubo, M., Aoki, Y., Tanaka, A., Yoshida, K., Ashida, H.:Green and black tea suppress hyperglycemia and insulin resistance by retaining the expression of glucose transporter 4 in muscle of high-fat diet-fed C57BL/6J mice, Journal of Agricultural and Food Chemistry, 58 (24), 12916-12923, (2011)
    34. Yamamoto, N., Kanamoto, Y., Ueda, M., Kawasaki, K., Fukuda, I., Ashida, H.:Anti-obese and anti-diabetic effects of ethanol extract of Artemisia princeps in C57BL/6 mice fed a high fat diet, Food & Function, 2 (1), 45-52, (2011)
    35. Kawabata, K., Sawada, K., Ikeda, K., Fukuda, I., Yamamoto, N., Ashida, H.:Prenylated chalcones 4-hydroxyderricin and xanthoangelol stimulate glucose uptake in skeletal muscle cells by inducing GLUT4 translocation, Molecular Nutrition & Food Research, 55 (3), 467-475, (2011)
    36. Nishiumi, S., Miyamoto, S., Kawabata, K., Ohnishi, K., Mukai, R., Murakami, A., Ashida, H., Terao, J.:Dietary flavonoids as cancer-preventive biofactors, Frontiers in Bioscience, S3, 1332-1362, (2011)
    37. Okazaki, F., Ogino, C., Kondo, A., Mikami, B., Kurebayashi, Y., Tsuruta, H.:Expression, crystallization and preliminary X-ray diffraction studies of thermostable β-1,3-xylanase from Thermotoga neapolitana strain DSM 4359, Acta Crystallographica Section F, 67, 779-78,(2011)
    38. Shinkawa, S., Okano, K., Yoshida, S., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A.:Improved homo l-lactic acid fermentation from xylose by abolishment of the phosphoketolase pathway and enhancement of the pentose phosphate pathway in genetically-modified xylose-assimilating Lactococcus lactis, Applied Microbiology and Biotechnology, 1537-1544, (2011)
    39. Suzuki, H., Takahashi, S., Osada, H., Yoshida, K.:Improvement of transformation efficiency by strategic circumvention of restriction barriers in Streptomyces griseus, Journal of Microbiology and Biotechnology, 21, 675-678, (2011)
    40. Matsuda, F., Furusawa, C., Kondo, T., Ishii, J., Shimizu, H., Kondo, A.:Engineering strategy of yeast metabolism for higher alcohol production, Microbial Cell Factories, 10(1), 70, (2011)
    41. Yamaoka, M., Osawa, S., Morinaga, T., Takenaka, S., Yoshida, K.:A cell factory of Bacillus subtilis engineered for the simple bioconversion of myo-inositol to scyllo-inositol, a potential therapeutic agent for Alzheimer's disease, Microbial Cell Factories, 10, 69, (2011)
    42. Fukuda, I., Tsutsui, M., Yoshida, T., Toda, T., Tsuda, T., Ashida, H.:Oral toxicological studies of black soybean (Glycine max) hull extract: acute studies in rats and mice, and chronic studies in mice, Food and Chemical Toxicology, 49(12), 3272-3278, (2011)
    43. Kanamoto, Y., Yamashita, Y., Nanba, F., Yoshida, T., Tsuda, T., Fukuda, I., Nakamura-Tsuruta, S., Ashida. H.:A black soybean seed coat extract prevents obesity and glucose intolerance by up-regulating uncoupling proteins and down-regulating inflammatory cytokines in high-fat diet-fed mice, Journal of Agricultural and Food Chemistry, 59(16), 8985-8993, (2011)
    44. Nakamura-Tsuruta, S., Yasuda, M., Nakamura, T., Shinoda, E., Furuyashiki, T., Kakutani, R., Takata, H., Kato, Y., Ashida, H.:Comparative analysis of carbohydrate-binding specificities of two anti-glycogen monoclonal antibodies using ELISA and surface plasmon resonance, Carbohydrate Research, 350, 49-54, (2011)
    45. Takenouchi, Y., Nakajima, H., Kanamaru, K., Takumi, S.:Characterization of three homoeologous cDNAs encoding chloroplast -targeted aminolevulinic acid dehydratase in common wheat, Journal of Interactive Plant Biology, 53, 942-50, (2011)
    46. Yoshida, H., Arai, S., Hara, K.Y., Yamada, R., Ogino, C., Fukuda, H., Kondo, A.:Efficient and direct glutathione production from raw starch using engineered Saccharomyces cerevisiae, Applied Microbiology and Biotechnology, 89(5), 1417-1422, (2011)
    47. Mizumoto, K., Hatano, H., Hirabayashi, C., Murai, K. Takumi, S.:Characterization of wheat Bell1-type homeobox genes in floral organs of alloplasmic lines with Aegilops crassa cytoplasm, BMC Plant Biology, 11, 2, (2011)
    48. Tanaka, T., Kawabata, H., Ogino, C., Kondo, A.:Creation of cellooligosaccharide-assimilating escherichia coil strain by displaying active beta-glucosidase on the cell surface via a novel anchor protein, Applied and Environmental Microbiology, 77(17), 6265-6270, (2011)
    49. Morita, H., Hasunuma, T., Vassileva M., Tsenkova, R., Kondo, A.:Near infrared spectroscopy as high-throughput technology for screening of xylose-fermenting recombinant Saccharomyces cerevisiae strains, Analytical Chemistry, 83(11), 4023-4029, (2011)
    50. Shibutani, T., Kitaura, T., Ohmukai, Y., Maruyama, T., Nakatsuka, S., Watabe, T., Matsuyama, H.: Membrane fouling properties of hollow fiber membranes prepared from cellulose acetate derivatives, Journal of Membrane Science, 376, 102-109, (2011)
    51. Takagi, R., Mulyati, S., Arahman, N., Ohmukai, Y., Maruyama, T., Matsuyama, H.:Time dependence of transport number ratio during electrodialysis process, Desalination and Water Treatment, 34, 25-31, (2011)
    52. Hao, Y., Moriya, A., Maruyama, T., Ohmukai, Y., Matsuyama, H.:Effect of metal ions on humic acid fouling of hollow fiber ultrafiltration membrane, Journal of Membrane Science, 376, 247-253, (2011)
    53. Fujii, A., Ohmukai, Y., Maruyama, T. Sotani, T., Matsuyama, H.:Preparation of DNA capsules cross-linked through NeutrAvidin-biotin interaction, Colloids Surf. A., 384, 529-535, (2011)
    54. Hashino, M., Hirami, K., Katagiri, T., Kubota, N., Ohmukai, Y., Ishigami, T. Maruyama, T., Matsuyama, H.:Effects of three natural organic matter types on cellulose acetate butyrate microfiltration membrane fouling, Journal of Membrane Science, 379, 233-238, (2011)
    55. Hashino, M., Katagiri, T., Kubota, N., Ohmukai, Y., Maruyama, T., Matsuyama, H.:Effect of surface roughness of hollow fiber membranes with gear-shaped structure on membrane fouling by sodium alginate, Journal of Membrane Science, 366, 389-397, (2011)
    56. Hashino, M., Katagiri, T., Kubota, N., Ohmukai, Y., Maruyama, T., Matsuyama, H.:Effect of membrane surface morphology on membrane fouling with sodium alginate, Journal of Membrane Science, 366, 258-265, (2011)

     

    総説・解説等

    1. 山本憲朗:「ショウガ科植物由来成分カルダモニンの糖取込促進作用について (特集 スパイスでヘルスケア その生理作用と効用)Aromatopia20510-12(2012)
    2. 蓮沼誠久近藤昭彦:「微生物機能学11微生物を利用して有限な化石資源から脱却する」三共出版119-133(2012)
    3. 山田亮祐蓮沼誠久近藤昭彦:「バイオマス分解酵素研究の最前線28セルラーゼ細胞表層提示酵母を用いたバイオマス変換」シーエムシー出版265-2712012
    4. 蓮沼誠久近藤昭彦:「バイオマス分解酵素研究の最前線序章2バイオマス分解酵素研究の新たな展開」シーエムシー出版6-92012
    5. Mukai, R., Terao, J., Shirai, Y., Saito, N., Ashida. H., :Determination of subcellular localization of flavonol in cultured cells by laser scanning, Laser Scanning, Theory and Applications, 215-232, (2011)
    6. Yamamoto, N., Ueda, M., Sato, T., Kawasaki, K., Sawada, K., Kawabata, K., Ashida, H.:Measurement of glucose uptake in cultured cells, Curr. Protoc. Pharmacol., 12(12.14), 1-22, (2011)
    7. 蓮沼誠久,近藤昭彦:「バイオマスからの効率的なバイオ燃料の生産技術」,ケミカルエンジニヤリング,56(9)5-12(2011)
    8. 近藤昭彦:「バイオエタノール製造技術の現状と課題」,生産と技術,63(2)8-13(2011)
    9. 吉田健一蓮沼誠久:「有用希少イノシトールのバイオアベイラビリティーとバイオコンバージョン生産生物工学会誌89(10)585-588,(2011
    10. 近藤昭彦:「細胞表層工学技術の広範な展開と合成生物工学の開拓によるバイオ燃料・グリーン化学品生産のための細胞工場の創製」,生物工学会誌,89(4) 154-160(2011)
    11. 蓮沼誠久,藍川晋平,和泉自泰,近藤昭彦:「微細藻類によるバイオリファイナリー」,生物工学会誌,89(4)181-183(2011)
    12. 大澤朗:「タンナーゼ活性を有する乳酸菌を利用した新規プロバイオティクスの開発」,腸内細菌学雑誌25巻,1号,1-5,(2011
    13. Mukai, R., Terao, J., Shirai, Y., Saito, N., Ashida, H.:Determination of subcellular localization of flavonol in cultured cells by laser scanning. Laser Scanning, Theory and Applications, 215-232, (2011)

     

    受賞等

    1. 天野仰,白井智量,松本佳子,平野淳一郎,高橋均,竹林のぞみ,森重敬,舘野俊博,古澤力,平沢敬,清水浩,和田光史:「イソプロピルアルコール高生産大腸菌の開発」(日本農芸化学会2012年度大会トピックス賞),2012.3.23
    2. Ogawa, R.:Effect of enzymatically synthesized glycogen on fat accumulation and lipid metabolism in mice fed a high-fat diet(日本フードファクター学会2011 International Conference on Food Factors <Travel Award>), 2012.1.30
    3. 保田倫子:財団法人農芸化学研究奨励会、第60回国際会議出席費補助金交付
    4. 岡崎文美:「Halomonas elongata を用いたバイオマス由来C5糖からの高効率エクトイン生産プロセスの開発」(第12回極限環境生物学会ポスター賞),2011.11.27
    5. Yamashita, Y., Natsume, M., Ashida, H.:Cacao liquor procyanidin extract suppresses hyperglycemia through promotion of glucose uptake accompanied by translocation of glucose transporter 4 in muscle」(2011 International Conference on Food Factors Travel Award, 2011.11.20
    6. 山下陽子,芦田均:「エピカテキン重合体であるプロシアニジンを高含有する組成物の肥満予防効果」(第8回日本カテキン学会 優秀プレゼンテーション賞), 2011.9.22
    7. Yasuda, M., Furuyashiki, T., Kakutani, R., Takata, H., Nakamura, T., Nakamura-Tsuruta, S., Ashida, H.:Metabolism and function of enzymatically synthesized glycogen in intestine(XI Asian Congress of Nutrition), 2011.7.13
    8. 保田倫子:「Metabolism and function of enzymatically synthesized glycogen in intestine」(財団法人農芸化学研究奨励会 第60回国際会議出席費補助金交付), 2011.7.13

     

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